Benfotiamine (S-benzoylthiamine-O-monophosphate) is a synthetic derivative of thiamin, belonging to the family of compounds known as "allithiamines." Benfotiamine is fat-soluble and thus more bioavailable and physiologically active than thiamin. Characteristic of the allithiamines is an open thiazole ring within the chemical structure of these thiamine-related compounds, making them fat (lipid) soluble. In contrast, thiamine, which is water soluble, has a closed thiazole ring. The lipid solubility of benfotiamine, conferred by this open ring, increases its bioavailablity. Benfotiamine is readily absorbed at higher doses, in contrast to absorption of water-soluble thiamin salts, which decreases at higher doses, due to saturation of absorption sites in the intestines. 1 In a double-blind, cross-over trial, comparing bioavailability of benfotiamine to that of thiamine in 12 subjects, benfotiamine caused an average 5-fold greater increase in blood thiamine levels than thiamin mononitrate, with a concomitant greater thiamine concentration in erythrocytes (red blood cells). 2 Benfotiamine readily passes through intestinal mucosal cells, where it is converted into physiologically active thiamine. Benfotiamine inceases blood levels of thiamine pyrophosphate (TPP), the primary thiamin co-enzyme.
Ingredients of Best Benfotiamine
Supplement
Facts
Serving Size: 1 capsules
Servings per container: 120 servings
Ingredients
Amount
%DV
Benfotiamine
150 mg
Other
Ingredients: modified cellulose (vegetarian capsule), cellulose, silicon dioxide.
Does Not Contain: milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, salt, or preservatives.
: Daily value not established.
Suggested Use for Best Benfotiamine
One capsule daily, with or without food.
Additional Information for Best Benfotiamine
Benefits
Benfotiamine raises the blood level of thiamine pyrophosphate (TPP), the
biologically active co-enzyme of thiamine.4*
Thiamine and its Co-enzyme, TPP
Thiamine (vitamin B1) plays an essential part in the metabolism of glucose,
through actions of it co-enzyme TPP (thiamine pyrophosphate). More information about Best Benfotiamine
Warning for Best Benfotiamine
Contains nothing other than listed ingredients.
Disclaimer
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, cure, mitigate, treat, or prevent any disease.
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within this web site have not been evaluated by the Food and Drug
Administration. These products are not intended to diagnose, cure,
mitigate, treat, or prevent any disease.
