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NOW Glucosamine/MSM/Arnica Liposome Lotion is a synergistic blend of joint and skin support factors delivered via liposome technology. Liposomes are bi-layered, membranous spheres that are similar in almost every way to small cells. They can carry almost any active ingredient, and can deliver their cargo all at once or release it slowly over time. Research for the use of liposomes for topical application was pioneered by Mezei and his colleagues during the early 1980's. Recent advances in liposome delivery systems have improved the ability of these phospholipid vessels to deliver these vital nutrients through the epidermis and deeper layers of tissue.