Grape seed extract by Foodscience Of Vermont. Grape seed extract that is standardized to yield 95 mg (95%) proanthocyanidins (PCOs) per 100 mg capsule. PCOs are a special class of water soluble bioflavonoids that are potent antioxidants. In some comparative tests, PCOs were found to be 50 times more potent than Vitamin E and 20 times more potent than Vitamin C. PCOs Beneficial Effects the release of histamine from mast cells thereby reducing the adverse effects of histamine. PCOs support capillary strength. Weak capillaries can contribute to bruising, elastin and collagen dysfunction, edema and circulatory insufficiencies. Grape seed is a dietary supplement to support Defense mechanism of body and circulatory functions and proper skin health.