Pau d’Arco has been used by shaman in Brazil for at least a thousand years. Its use gradually spread to other parts of South America and beyond. Kallawaya tribal healers of Bolivia and Brazil call this bark tea “tajibo.” In Peru a tea made from the inner bark, known as “tarota,” is used by tribal healers of the Asháninka, Campas and Inca tribes. Pau d’Arco tea is also used traditionally by the Huastec Mayan people of Mexico. Modern researchers have largely focused on isolated constituents of Pau d’Arco, particularly its naphthoquinones including lapachol and anthraquinones including tabebuin, though the combined action of all of its constituents in simple dosage forms like hot tea have proven superior to the actions of any isolated chemicals.