SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reaqctions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can Enhance to temorarily alleviate aches and Discomforts resulting from overexterion or stress. Therefore, SAMe is an all natural product that can be part of a nutritional program for Discomfort management. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in the regulation of mood. NOW SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.