TMG 500 contains Trimethylglycine (TMG, also known as anhydrous betaine), a highly effective methyl donor extracted from sugar beets. Methyl donors, such as TMG and folic acid, are required for converting homocysteine back into methionine and for the accurate synthesis of DNA and RNA, which is essential for the production of normal cells. Methylation is inhibited by inadequately functioning key enzymes, excessive protein and fat intake, poor diet, inadequate intake of methyl groups, coffee, alcohol or by smoking. Impairment of methylation results in abnormal cell synthesis and elevated levels of homocysteine, a toxic amino acid and a serious health risk.